WP6 Decolonization in ICU

The R-GNOSIS work package 6 comprises a multicenter study in 15 European intensive care units to evaluate the ecological effects of 3 decontamination strategies. The strategies are selective oropharyngeal decontamination with antibiotics, oropharyngeal decontamination with antiseptics and selective digestive tract decontamination with antibiotics. The effect of these strategies on the presence of multi drug resistant gram negative bacteria (MDR GNB) will be the primary objective of the study.