WP7 Microbiology

The overall objective of WP7 is to provide microbiological support to the clinical trials (WPs 2-6) and analyze the quantitative changes and within-host dynamics of MDR-GNB in the presence and absence of antibiotic selection pressure and gut decolonization and to study the emergence, persistence, resistance mechanisms, and clonal relationships of MDR-GNB as pathogens or commensals in the human gut microbiome.