Publications

Journal of Clinical Microbiology, 52(5), 1 May 2014, pp 1741-44, doi: 10.1128/JCM.03614-13
Intensive Care Medicine, 40(4), 1 April 2014, pp 564–571, doi: 10.1007/s00134-014-3225-8
Expert Opinion on Therapeutic Targets, 18(8), 1 August 2014, pp 851-61, doi: 10.1517/14728222.2014.925881

Project Partners

R-GNOSIS is coordinated by Marc Bonten (UMC Utrecht) and brings together a multidisciplinary team with complementary expertise of clinicians, microbiologists and epidemiologists, infectious disease specialists, caregivers in inpatient care and mathematical modellers. The R-GNOSIS consortium is made of 19 partners from 9 countries which include United Kingdom, Denmark, Germany, Netherlands, Belgium, France, Spain, Switzerland and Israel.

Organizational Activities

The UMC Utrecht is an internationally renowned research and teaching hospital with 1,200 beds and all medical specialties represented. Within the Department of Medical Microbiology and the “Julius Centre for Health Care Epidemiology and Primary Care” >50 researchers from different medical specialties collaborate in studying antibiotic resistance, epidemiology of infectious diseases and ICU-acquired infections, applying molecular, microbiological, epidemiological and theoretical methods. Both departments harbour extensive experience with large-scale multi-centre intervention trials and epidemiological analyses of large patient databases. The investigators are already coordinating or participating in several international EC-funded projects (GRACE, MOSAR, ACE, CONCORD, SATURN). The Julius Centre for Health Care Epidemiology and Primary Care also hosts the data management department that has successfully coordinated data management in large (and complex) EC-funded projects as GRACE and MOSAR.

Role in the Project

Key Personnel

Marc Bonten, MD, PhD, is professor of molecular epidemiology of infectious diseases, head of the department of Medical Microbiology and head of Infectious Disease research within the Julius Centre for Health Sciences and Primary Care. He has extensive experience in large-scale multi-centre intervention trials and epidemiological analyses of large patient databases in ICUs and antibiotic resistance. He has published >250 papers in peer-reviewed scientific journals and is associate editor of Intensive Care Medicine. - no image description is available -
Bastiaan Wittekamp, MD, is a PhD candidate coordinating the “R-GNOSIS: decolonisation strategies in intensive care” study (WP6), under supervision of Marc Bonten and Christian Brun-Buisson. - no image description is available -
Frank Leus, BSc, Lead on R-GNOSIS WP9, Manager of ISO certified Data Management department at the UMC Utrecht. He has extensive experience in large scale data management of investigator initiated and pharmaceutical industry sponsored international clinical research. WP leader of 3 Data Management WPs of EU funded projects and involved in data management of several other EU funded projects. - no image description is available -
Joost Schotsman, MSc, Senior Data Manager and is coordinating the R-GNOSIS WP9. He has extensive experience in Data Management of clinical trials and actively involved in several EU funded projects. - no image description is available -